PGD is a genetic testing procedure used during IVF to test embryos for specific genetic diseases before implantation. Unlike PGS, which screens for chromosomal abnormalities, PGD focuses on identifying specific genetic mutations that can lead to hereditary conditions, such as cystic fibrosis, sickle cell anemia, or Huntington’s disease. PGD allows couples at risk of passing on a genetic disorder to choose embryos that are free from the disease, greatly reducing the risk of transmission.
During IVF, embryos are created through fertilization and cultured for a few days. A biopsy is performed on day 5 or 6, where a few cells are removed from the embryo. The DNA from these cells is then tested for specific genetic mutations or inherited conditions. Only embryos that are free from the genetic disorder are selected for transfer into the uterus. PGD can be performed on embryos for a wide range of genetic disorders, providing families with peace of mind that the child will not inherit certain diseases.
PGD is a genetic testing procedure used during IVF to test embryos for specific genetic diseases before implantation. Unlike PGS, which screens for chromosomal abnormalities, PGD focuses on identifying specific genetic mutations that can lead to hereditary conditions, such as cystic fibrosis, sickle cell anemia, or Huntington’s disease. PGD allows couples at risk of passing on a genetic disorder to choose embryos that are free from the disease, greatly reducing the risk of transmission.
PGD is highly successful in identifying embryos free of genetic diseases, which greatly increases the chances of a healthy pregnancy and baby. The success rate of PGD depends on the specific disorder being tested for, but overall IVF success rates with PGD are similar to IVF with PGS, typically ranging from 35% to 50% per cycle.
